What's Best Antibiotic Treatment To Epididymitis Or Epididymal Cyst

 

Epididymitis treatment with antibiotics is controversial. Some have found benefits in symptoms, while others have questioned the utility of a trial of antibiotics. Antibiotics are known to have anti-inflammatory properties and this has been suggested as an explanation for their partial efficacy in treating Epididymitis Or Epididymal Cyst. Antibiotics such as fluoroquinolones, tetracyclines and macrolides have direct anti-inflammatory properties in the absence of infection, blocking inflammatory chemical signals (cytokines) such as interleukin-1 (IL-1), interleukin-8 and tumor necrosis factor (TNF).

 

In spite of controversies, antibiotics are the first line of treatment in both the acute epididymitis and chronic epididimitis. And antibiotic therapy should cover Chlamydia trachomatis, Neisseria gonorrhoeae, and Escherichia coli, the most common infecting pathogens. Doctors may provide consultation on appropriate antibiotic therapy and dosing. Appropriate antibiotics should be used on the base of the microbe causing the infection. To choose a bactericidal antibiotic (kills bacteria, e.g., a fluoroquinolone antibiotic) or to use a bacteriostatic antibiotic (slows bacterial growth, e.g. tetracycline) depends on the symptoms of epididymitis.

 

-If an enteric organism such as E. coli is the suspected cause of epididymo-orchitis, ofloxacin or levofloxacin are the preferred antibiotic, as they have excellent penetration into the testes.  In a review of multiple studies, levofloxacin was found to reach prostatic fluid concentrations 5.5 times higher than Ciprofloxacin, indicating a greater ability to penetrate the epididymis. And ofloxacin usually be used among older males.

 

-For cases caused by gonorrhoeae and chlamydia, the treatment of choice is often azithromycin which is often used to treat sexually transmitted diseases and works to stop bacterial growth and Ofloxacin which penetrates the prostate well and is effective against C trachomatis. Doxycycline may be used as an alternative to azithromycin and is recommended in those who are young and sexually active. 

 

-As to children, fluoroquinolones and doxycycline are best avoided. Since bacteria that cause urinary tract infections are what causes epididymitis in children, co-trimoxazole or suited penicillins (for example, cephalexin) can be used.

 

Antibiotics usually resolve acute epididymitis infections in a very short time, however a minimum of two to four weeks of antibiotic therapy is recommended to eradicate the offending organism completely. In chronic epididymitis, a four- to six-week course of antibiotics may be prescribed to ensure the complete eradication of any possible bacterial cause, especially the various chlamydiae.